Henry (Pathé) Lehrman started out at Biograph, then went to Keystone with Mack Sennett, then left Sennett to found L-KO (Lehrman Knock-Out) Komedies. He left L-KO to produce Sunshine Comedies for Fox. Sunshine Comedies frequently featured pretty girls and lions. Case in point: "Wild Women and Tame Lions."
Bud Fisher's Mutt and Jeff was the most popular comic strip in America for many years. Augustus Mutt and Jeff had many timely adventures.